International Consensus on Antinuclear Antibody em Portugal
نویسندگان
چکیده
Introdução: A pesquisa de autoanticorpos em células HEp-2 através imunofluorescência indireta é o teste padrão atualmente aceite como a ferramenta central para diagnóstico das doenças autoimunes sistémicas. O International Consensus on Antinuclear Antibody (ANA) Patterns tem objetivo principal alcançar um consenso na nomenclatura e descrição dos diferentes padrões morfológicos anticorpos antinucleares. Este trabalho ampliar projeto do ANA forma estabelecer Portugal sua nomenclatura, procurando contribuir harmonização no autoimune promover qualidade diagnóstica nas reumáticas sistémicas autoimunes.Material Métodos: Os laboratórios participantes identificaram cada designação citoplasmático nuclear (incluindo código anti-célula), fizeram corresponder uma respetiva portuguesa uso. resultados foram agregados serviram base ao da nomenclatura. Seguiram-se reuniões consenso, num processo iterativo até à redação proposta final consensualizada.Resultados: concordância prévia entre era superior 75% 23 total 29 anti-célula. grau que laboratório está alinhado com referência internacional varia 22,1% 100%. Foi possível elaborar versão consensualizada Portugal.Discussão: Existia boa Patterns, mas diferenças importantes algumas traduções terminologia. estudo realça necessidade colaboração inequívoca laboratoriais.Conclusão: mostra potencial positivo gerar consensos contribuam melhoria acompanhamento doentes.
منابع مشابه
Report of the First International Consensus on Standardized Nomenclature of Antinuclear Antibody HEp-2 Cell Patterns 2014–2015
During the 12th International Workshop on Autoantibodies and Autoimmunity held in Sao Paulo, Brazil, on August 28, 2014, a full day session was devoted to establishing a consensus on the nomenclature of staining patterns observed in the antinuclear antibody (ANA) indirect immunofluorescence test on HEp-2 cells. The current report summarizes the collective agreements with input from the host Bra...
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ژورنال
عنوان ژورنال: Acta Médica Portuguesa
سال: 2021
ISSN: ['0870-399X', '1646-0758']
DOI: https://doi.org/10.20344/amp.13121